

Angioedema (buildup of fluid deep in your skin or underneath your skin).It also includes abnormally heavy menstrual flow, blood in your urine, or black tarry stools. This includes bleeding from minor cuts, nose or mouth bleeding, and pinpoint red spots on your skin. Decreased platelet and white blood cell production.Hallucinations (seeing or hearing things that aren’t there).sticking your tongue out uncontrollably.uncontrollable neck muscle contractions causing your head to twist or turn to one side.

uncontrollable upward staring, and eye and lid twitching.Extrapyramidal symptoms (uncontrollable movements).Serious side effects and their symptoms can include the following: Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effectsĬall your doctor right away if you have serious side effects. If they’re more severe or don’t go away, talk to your doctor or pharmacist. If these effects are mild, they may go away within a few days or a couple of weeks. The more common side effects that can occur with promethazine oral tablet include: This drug also works to reduce stimulation of the part of your brain that sends signals to make you vomit. This is because histamine helps regulate wakefulness and helps to keep you alert and your senses heightened. Histamine is normally released when you’re exposed to things you’re allergic to, such as pollen, dander, mold, or chemicals.īy preventing the release of histamine, this drug causes sleepiness and helps with pain control. Promethazine works by preventing the release of a substance called histamine from certain cells in your body. These drugs are often used to treat similar conditions. A class of drugs is a group of medications that work in a similar way. Promethazine belongs to a class of drugs called phenothiazines. That means you may need to take it with other medications. This drug may be used as part of a combination therapy. It’s also used as a sleep aid, including before and after surgery. Promethazine is used to treat several conditions, including allergies, motion sickness, nausea and vomiting, anxiety before surgery, and pain after surgery. Generic drugs usually cost less than brand-name versions. Promethazine oral tablet is only available as a generic drug. It comes as an oral tablet, an oral solution, an injectable solution, and a rectal suppository. Dementia warning: Research has indicated that this type of medication can cause effects similar to those caused by drugs called anticholinergics.Symptoms can include fever, rigid muscles, mental changes, changes in pulse or blood pressure, fast heartbeat, increased sweating, or irregular heart rhythm. Neuroleptic malignant syndrome warning: The use of this drug is linked with neuroleptic malignant syndrome.Don’t drive a car or use machinery until you know how this drug affects you. Extreme drowsiness warning: This drug may cause extreme drowsiness.

Also, this drug should not be used in children who are taking other drugs that may cause slowed breathing. Caution should be used when giving this drug to children older than 2 years. In children this age, this drug may cause slowed breathing that may result in death. It should not be used in children younger than 2 years.
A black box warning alerts doctors and patients about drug effects that may be dangerous. This is the most serious warning from the Food and Drug Administration (FDA). FDA warning: Breathing problems in young children
